An Integrated Strategy Including Chemical Profiling, Network Pharmacology And Experimental Evaluation Was Used To Investigate The Effects Of Rubia Yunnanensis Water Decoction On Vascular Dementia

RY-W effectively ameliorates VaD pathology by exerting anti-inflammatory and anti-apoptotic effects. These findings highlight the involvement of ALB and the PI3K-Akt signaling pathway in the therapeutic action of RY-W, supporting its potential as a treatment for vascular dementia.

Publication Details

Journal
Pakistan Journal of Pharmaceutical Sciences
Published
2026-02-23
DOI
https://doi.org/10.36721/pjps.2026.39.5.reg.14029.1
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

An Integrated Strategy Including Chemical Profiling, Network Pharmacology And Experimental Evaluation Was Used To Investigate The Effects Of Rubia Yunnanensis Water Decoction On Vascular Dementia

Pakistan Journal of Pharmaceutical Sciences
Neurological Disease Mechanisms and Treatments
article

An Integrated Strategy Including Chemical Profiling, Network Pharmacology And Experimental Evaluation Was Used To Investigate The Effects Of Rubia Yunnanensis Water Decoction On Vascular Dementia

article en

Abstract

RY-W effectively ameliorates VaD pathology by exerting anti-inflammatory and anti-apoptotic effects. These findings highlight the involvement of ALB and the PI3K-Akt signaling pathway in the therapeutic action of RY-W, supporting its potential as a treatment for vascular dementia.

Pakistan Journal of Pharmaceutical SciencesVol. 39(5)
Clean water and sanitation
Openalex Percentile: Top 26%
Neurological Disease Mechanisms and Treatments
DOIOpen Access PDFOpenAlex
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An Integrated Strategy Including Chemical Profiling, Network Pharmacology And Experimental Evaluation Was Used To Investigate The Effects Of Rubia Yunnanensis Water Decoction On Vascular Dementia · Pakistan Journal of Pharmaceutical Sciences (2026) | TGRS Research Map | TGRS