Neohesperidin Dihydrochalcone-Pyruvic Acid Deep Eutectic Solvent: A Novel Tyrosinase Inhibitor for Enhanced Transdermal Delivery

This study synthesizes a novel therapeutic deep eutectic solvent (THEDES) comprising neohesperidin dihydrochalcone (NHDC) and pyruvic acid (PA) to overcome NHDC’s poor solubility and optimize its transdermal delivery as a...

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Publication Details

Journal
New Journal of Chemistry
Published
2026-01-01
DOI
https://doi.org/10.1039/d5nj04586j
Primary Topic
melanin and skin pigmentation
Type
article
Field-Weighted Citation Impact
0.00
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article

Neohesperidin Dihydrochalcone-Pyruvic Acid Deep Eutectic Solvent: A Novel Tyrosinase Inhibitor for Enhanced Transdermal Delivery

Liyong Du, J.C. Yang, Qin Wang, Wenbo Li et al.
New Journal of Chemistry
melanin and skin pigmentation
article

Neohesperidin Dihydrochalcone-Pyruvic Acid Deep Eutectic Solvent: A Novel Tyrosinase Inhibitor for Enhanced Transdermal Delivery

Liyong Du, J.C. Yang, Qin Wang, Wenbo Li, Shuxian Chen
article en

Abstract

This study synthesizes a novel therapeutic deep eutectic solvent (THEDES) comprising neohesperidin dihydrochalcone (NHDC) and pyruvic acid (PA) to overcome NHDC’s poor solubility and optimize its transdermal delivery as a...

New Journal of Chemistry
Openalex Percentile: Top 9%
melanin and skin pigmentation
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Neohesperidin Dihydrochalcone-Pyruvic Acid Deep Eutectic Solvent: A Novel Tyrosinase Inhibitor for Enhanced Transdermal Delivery — Liyong Du, J.C. Yang, et al. · New Journal of Chemistry (2026) | TGRS Research Map | TGRS