Integrating Explainable Artificial Intelligence In Healthcare: Models, Applications, And Challenges

This paper will explore the role of XAI in advancing healthcare systems by examining various explain ability models and techniques, including feature attribution methods, model-agnostic approaches, and interpretable machine learning frameworks. It will highlight key applications of XAI in medical imaging, clinical decision support systems, disease prediction, and personalized medicine, where interpretability will be crucial for ensuring reliability and accountability. Furthermore, the study will discuss emerging challenges such as the trade-off between model accuracy and interpretability, data privacy concerns, lack of standardized evaluation metrics, and integration barriers within real-world clinical settings. Ethical considerations and regulatory requirements will also be analysed to understand the broader implications of deploying XAI in HealthCare. The paper will conclude by emphasizing the need for robust, scalable, and clinically validated XAI solutions that will bridge the gap between complex AI models and human understanding. Future research will focus on developing hybrid models, improving user-centric explanations, and fostering interdisciplinary collaboration to ensure the safe and effective adoption of explainable AI in healthcare.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-01
DOI
https://doi.org/10.5281/zenodo.19218726
Primary Topic
Explainable Artificial Intelligence (XAI)
Type
article
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article

Integrating Explainable Artificial Intelligence In Healthcare: Models, Applications, And Challenges

Dr. Brij Mohan Goel, Ms. Babita
Zenodo (CERN European Organization for Nuclear Research)
Explainable Artificial Intelligence (XAI)
article

Integrating Explainable Artificial Intelligence In Healthcare: Models, Applications, And Challenges

Dr. Brij Mohan Goel, Ms. Babita
article en

Abstract

This paper will explore the role of XAI in advancing healthcare systems by examining various explain ability models and techniques, including feature attribution methods, model-agnostic approaches, and interpretable machine learning frameworks. It will highlight key applications of XAI in medical imaging, clinical decision support systems, disease prediction, and personalized medicine, where interpretability will be crucial for ensuring reliability and accountability. Furthermore, the study will discuss emerging challenges such as the trade-off between model accuracy and interpretability, data privacy concerns, lack of standardized evaluation metrics, and integration barriers within real-world clinical settings. Ethical considerations and regulatory requirements will also be analysed to understand the broader implications of deploying XAI in HealthCare. The paper will conclude by emphasizing the need for robust, scalable, and clinically validated XAI solutions that will bridge the gap between complex AI models and human understanding. Future research will focus on developing hybrid models, improving user-centric explanations, and fostering interdisciplinary collaboration to ensure the safe and effective adoption of explainable AI in healthcare.

Zenodo (CERN European Organization for Nuclear Research)
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Openalex Percentile: Top 10%
Explainable Artificial Intelligence (XAI)
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Integrating Explainable Artificial Intelligence In Healthcare: Models, Applications, And Challenges — Dr. Brij Mohan Goel, Ms. Babita · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS