Takotsubo Syndrome Complicated by Dynamic Left Ventricular Outflow Tract Obstruction After Left Bundle Branch Area Pacing

Left bundle branch area pacing (LBBAP) has emerged as a physiologic pacing strategy that better preserves ventricular synchrony compared with traditional right ventricular pacing (RVP).1,2 By engaging the native conduction system, LBBAP is associated with narrower QRS duration and improved hemodynamic performance.3,4 Although generally safe, the transseptal lead approach carries procedure-specific risks,5-7 including septal injury, coronary trauma, and rare stress-related cardiomyopathy. Takotsubo syndrome (TTS) has been reported after pacemaker implantation,8 including LBBAP.

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Journal
HeartRhythm Case Reports
Published
2026-03-01
DOI
https://doi.org/10.1016/j.hrcr.2026.03.017
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
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article

Takotsubo Syndrome Complicated by Dynamic Left Ventricular Outflow Tract Obstruction After Left Bundle Branch Area Pacing

Fabrizio De Rosa, Giovanni Tortorella, Andrea Botti, Paolo Pastori et al.
HeartRhythm Case Reports
Takotsubo Cardiomyopathy and Associated Phenomena
article

Takotsubo Syndrome Complicated by Dynamic Left Ventricular Outflow Tract Obstruction After Left Bundle Branch Area Pacing

Fabrizio De Rosa, Giovanni Tortorella, Andrea Botti, Paolo Pastori, Matteo Bertini, Francesco Vitali
article en

Abstract

Left bundle branch area pacing (LBBAP) has emerged as a physiologic pacing strategy that better preserves ventricular synchrony compared with traditional right ventricular pacing (RVP).1,2 By engaging the native conduction system, LBBAP is associated with narrower QRS duration and improved hemodynamic performance.3,4 Although generally safe, the transseptal lead approach carries procedure-specific risks,5-7 including septal injury, coronary trauma, and rare stress-related cardiomyopathy. Takotsubo syndrome (TTS) has been reported after pacemaker implantation,8 including LBBAP.

HeartRhythm Case Reports
University of Ferrara (IT), Azienda Unita' Sanitaria Locale di Parma (IT)
Good health and well-being
Openalex Percentile: Top 18%
Takotsubo Cardiomyopathy and Associated Phenomena
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Takotsubo Syndrome Complicated by Dynamic Left Ventricular Outflow Tract Obstruction After Left Bundle Branch Area Pacing — Fabrizio De Rosa, Giovanni Tortorella, et al. · HeartRhythm Case Reports (2026) | TGRS Research Map | TGRS