Bioinspired photoenzymatic cascade enabled by a bifunctional arylformamidase for efficient synthesis of L-kynurenine derivatives

L-Kynurenine (L-Kyn) serves as a pivotal metabolite and a versatile building block for numerous bioactive natural products and pharmaceuticals. However, conventional synthetic routes are often hampered by poor step economy...

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Publication Details

Journal
Green Chemistry
Published
2026-01-01
DOI
https://doi.org/10.1039/d6gc00950f
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Bioinspired photoenzymatic cascade enabled by a bifunctional arylformamidase for efficient synthesis of L-kynurenine derivatives

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Green Chemistry
Tryptophan and brain disorders
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Bioinspired photoenzymatic cascade enabled by a bifunctional arylformamidase for efficient synthesis of L-kynurenine derivatives

Xinpeng Lü, Yijian Rao, Zhenbo Yuan, Xiaorui Chen, Meiling Liu, Chengyue Miao, Min He, Wenrui Huang, Changtong Zhu, Changmei Liu
article en

Abstract

L-Kynurenine (L-Kyn) serves as a pivotal metabolite and a versatile building block for numerous bioactive natural products and pharmaceuticals. However, conventional synthetic routes are often hampered by poor step economy...

Green Chemistry
Openalex Percentile: Top 22%
Tryptophan and brain disorders
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