Pharmacokinetic Evaluation Of Etoricoxib 120mg Tablets In Healthy Human Pakistani Volunteers: In-Vivo In-Silico Bridging For Bioequivalence

The study demonstrated comparable systemic exposure and confirmed bioequivalence between the locally manufactured and innovator etoricoxib formulations in the Pakistani population. PBPK modeling provided supportive evidence of formulation similarity and model adequacy.

Publication Details

Journal
Pakistan Journal of Pharmaceutical Sciences
Published
2026-03-08
DOI
https://doi.org/10.36721/pjps.2026.39.5.reg.15284.1
Primary Topic
Inflammatory mediators and NSAID effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacokinetic Evaluation Of Etoricoxib 120mg Tablets In Healthy Human Pakistani Volunteers: In-Vivo In-Silico Bridging For Bioequivalence

Pakistan Journal of Pharmaceutical Sciences
Inflammatory mediators and NSAID effects
article

Pharmacokinetic Evaluation Of Etoricoxib 120mg Tablets In Healthy Human Pakistani Volunteers: In-Vivo In-Silico Bridging For Bioequivalence

article en

Abstract

The study demonstrated comparable systemic exposure and confirmed bioequivalence between the locally manufactured and innovator etoricoxib formulations in the Pakistani population. PBPK modeling provided supportive evidence of formulation similarity and model adequacy.

Pakistan Journal of Pharmaceutical SciencesVol. 39(5)
Good health and well-being
Openalex Percentile: Top 8%
Inflammatory mediators and NSAID effects
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Pharmacokinetic Evaluation Of Etoricoxib 120mg Tablets In Healthy Human Pakistani Volunteers: In-Vivo In-Silico Bridging For Bioequivalence · Pakistan Journal of Pharmaceutical Sciences (2026) | TGRS Research Map | TGRS