Insertion of SnCl₂ into the Pd–Cl Bond: Mechanistic Elucidation and Antitumor Evaluation of Trichlorostannyl Palladium-NHC Allyl Complexes in Ovarian Cancer Models

The development of effective and selective metal-based chemotherapeutics remains a central challenge in ovarian cancer treatment, particularly in addressing resistance to platinum agents. Herein, we report the design, synthesis, and...

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Publication Details

Journal
Dalton Transactions
Published
2026-01-01
DOI
https://doi.org/10.1039/d6dt00680a
Primary Topic
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
Type
article
Field-Weighted Citation Impact
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article

Insertion of SnCl₂ into the Pd–Cl Bond: Mechanistic Elucidation and Antitumor Evaluation of Trichlorostannyl Palladium-NHC Allyl Complexes in Ovarian Cancer Models

Vincenzo Canzonieri, Laura Orian, Flavio Rizzolio, Eleonora Botter et al.
Dalton Transactions
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
article

Insertion of SnCl₂ into the Pd–Cl Bond: Mechanistic Elucidation and Antitumor Evaluation of Trichlorostannyl Palladium-NHC Allyl Complexes in Ovarian Cancer Models

Vincenzo Canzonieri, Laura Orian, Flavio Rizzolio, Eleonora Botter, Fabiano Visentin, Enrico Cavarzerani, Matteo Forner, Alessandro Rubbi, Valentina Lauteri, Thomas Scattolin, Valentina Gandin, Nicola Demitri
article en

Abstract

The development of effective and selective metal-based chemotherapeutics remains a central challenge in ovarian cancer treatment, particularly in addressing resistance to platinum agents. Herein, we report the design, synthesis, and...

Dalton Transactions
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N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
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