Esketamine And Postoperative Cognitive Dysfunction In Aged Mice: Role Of The SIRT3/AMPK/MTOR Pathway

Esk appears to regulate SIRT3/AMPK/mTOR pathway to inhibit neuroinflammation and improve mitochondrial dysfunction, thereby mitigating POCD in aged mice.

Publication Details

Journal
Pakistan Journal of Pharmaceutical Sciences
Published
2026-03-08
DOI
https://doi.org/10.36721/pjps.2026.39.5.reg.15336.1
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Esketamine And Postoperative Cognitive Dysfunction In Aged Mice: Role Of The SIRT3/AMPK/MTOR Pathway

Pakistan Journal of Pharmaceutical Sciences
Intensive Care Unit Cognitive Disorders
article

Esketamine And Postoperative Cognitive Dysfunction In Aged Mice: Role Of The SIRT3/AMPK/MTOR Pathway

article en

Abstract

Esk appears to regulate SIRT3/AMPK/mTOR pathway to inhibit neuroinflammation and improve mitochondrial dysfunction, thereby mitigating POCD in aged mice.

Pakistan Journal of Pharmaceutical SciencesVol. 39(5)
Openalex Percentile: Top 8%
Intensive Care Unit Cognitive Disorders
DOIOpen Access PDFOpenAlex
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Esketamine And Postoperative Cognitive Dysfunction In Aged Mice: Role Of The SIRT3/AMPK/MTOR Pathway · Pakistan Journal of Pharmaceutical Sciences (2026) | TGRS Research Map | TGRS