Advances in Liver Injury Drug Development: Integrating Natural Small Molecules, Genomic Targets, and Network Pharmacology

In summary, the convergence of natural products, target-specific therapeutic strategies, and network pharmacology represents a promising direction in liver injury drug development. By addressing current limitations and harnessing emerging technologies, future research has the potential to fully realize the therapeutic value of these integrated approaches, ultimately advancing the development of more effective and personalized treatments for liver diseases.

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Publication Details

Journal
Current Pharmaceutical Analysis
Published
2026-03-01
DOI
https://doi.org/10.1016/j.cpan.2026.03.008
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
0.00
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article

Advances in Liver Injury Drug Development: Integrating Natural Small Molecules, Genomic Targets, and Network Pharmacology

Man Zhao, Siying Li, Shen Shen
Current Pharmaceutical Analysis
Drug-Induced Hepatotoxicity and Protection
article

Advances in Liver Injury Drug Development: Integrating Natural Small Molecules, Genomic Targets, and Network Pharmacology

Man Zhao, Siying Li, Shen Shen
article en

Abstract

In summary, the convergence of natural products, target-specific therapeutic strategies, and network pharmacology represents a promising direction in liver injury drug development. By addressing current limitations and harnessing emerging technologies, future research has the potential to fully realize the therapeutic value of these integrated approaches, ultimately advancing the development of more effective and personalized treatments for liver diseases.

Current Pharmaceutical Analysis
First Affiliated Hospital of Zhengzhou University (CN)
Openalex Percentile: Top 9%
Drug-Induced Hepatotoxicity and Protection
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