Impaired Left Atrial Strain is Associated with New-onset Atrial Fibrillation and Adverse Clinical Outcomes in Primary Care Patients
Atrial fibrillation diagnosis5-year follow-up period 216 with AF 216 age and sex matched controls Case-control study Is LA strain associated with new-onset atrial fibrillation?127 patients with new-onset AF and complete follow-up data LA strain capture Is LA strain associated with heart failure hospitalization, stroke, myocardial infarction, all-cause mortality in new-onset AF patients?Follow-up Component Case-control Component Impaired Left Atrial Strain is Associated with New-onset Atrial Fibrillation and Adverse Clinical Outcomes in Primary Care Patients Two -part study within a longitudinal, primary care cohort:Conclusion: In a primary care cohort, impaired LA strain was associated with both new-onset AF and adverse clinical outcomes after AF diagnosis, independent of traditional risk factors and LA size.These findings support the potential role of LA strain for AF risk stratification and subsequent clinical outcomes.
Authors
- Dana Cramariuc (ORCID: https://orcid.org/0000-0002-1593-2017)
- Jonathan Passeri (ORCID: https://orcid.org/0000-0003-2465-2460)
- Ygal Plakht (ORCID: https://orcid.org/0000-0003-0898-9776)
- Jason A. Sherer (ORCID: https://orcid.org/0000-0002-0946-9169)
- Shani Dahan (ORCID: https://orcid.org/0000-0003-4536-9701)
- Rasmus Bach Sindre (ORCID: https://orcid.org/0009-0001-2342-8849)
- Evin Yucel
- Shaan Khurshid
- Mostafa Amer Al-Alusi
- Judy Hung
- Steven A. Lubitz
- Michael H. Picard
- Patrick T. Ellinor
Institutions
- Broad Institute (US)
- Ben-Gurion University of the Negev (IL)
- Harvard University (US)
- Boston Foundation (US)
- Massachusetts General Hospital (US)
- University of Bergen (NO)
- Mass General Brigham (US)
Publication Details
- Journal
- Heart Rhythm O2
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1016/j.hroo.2026.03.021
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00