Comparison of 2% lidocaine and 0.5% bupivacaine with 2% lidocaine and 0.75% ropivacaine in peribulbar block for cataract surgery

Purpose: To compare the efficacy of 2% lidocaine and 0.5% bupivacaine with 2% lidocaine and 0.75% ropivacaine in peribulbar block for cataract surgery. To compare the duration for onset of sensory and motor blockade between the two groups. To find out the postoperative analgesia provided by 0.5% bupivacaine and 0.75% ropivacaine. Methods: A total of 80 patients were included in the study. After obtaining informed and written consent from patient, we randomized patients into two groups. Group B received 5 mL (1:1 mixture) of 0.5% Bupivacaine (ANAWIN 0.5%, NEON LABORATORIES LTD), 2% Lidocaine (XYLOCAINE ® 2%, AKUMS DRUGS and PHARMACEUTICALS LTD), 1500IU of Hyaluronidase (HYNIDASE, SHREYAS LIFE SCIENCES PVT LTD) while group R received 5 mL (1:1 mixture) 0.75% Ropivacaine (ROPIN 0.75%, NEON LABORATORIES LTD), 2% lidocaine, 1500IU of Hyaluronidase. Results: In this study of 80 patients undergoing small incision cataract surgery, Group B received a bupivacaine-lidocaine-hyaluronidase mixture, while Group R received a ropivacaine-lidocaine-hyaluronidase mixture for peribulbar block. Ropivacaine showed statistically significant advantages in faster motor block onset, lower IOP after 10 min, and longer analgesia duration, with no difference in sensory block onset. Thus, ropivacaine appears to be a safer and effective alternative to bupivacaine in peribulbar anesthesia for cataract surgery. Conclusion: The analysis showed that 0.75% Ropivacaine recorded an earlier onset of motor block, low IO P value post block, and longer duration of analgesia than 0.5% Bupivacaine that was statistically significant. Hence, Ropivacaine can be used as a safer alternative for Bupivacaine in peribulbar block for cataract Surgery.

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Journal
Journal of Dr NTR University of Health Sciences
Published
2026-01-01
DOI
https://doi.org/10.4103/jdrntruhs.jdrntruhs_95_25
Primary Topic
Intraocular Surgery and Lenses
Type
article
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article

Comparison of 2% lidocaine and 0.5% bupivacaine with 2% lidocaine and 0.75% ropivacaine in peribulbar block for cataract surgery

Doni Akshitha, Pakalapati Pradeep, Surya M. D. Pusapati
Journal of Dr NTR University of Health Sciences
Intraocular Surgery and Lenses
article

Comparison of 2% lidocaine and 0.5% bupivacaine with 2% lidocaine and 0.75% ropivacaine in peribulbar block for cataract surgery

Doni Akshitha, Pakalapati Pradeep, Surya M. D. Pusapati
article en

Abstract

Purpose: To compare the efficacy of 2% lidocaine and 0.5% bupivacaine with 2% lidocaine and 0.75% ropivacaine in peribulbar block for cataract surgery. To compare the duration for onset of sensory and motor blockade between the two groups. To find out the postoperative analgesia provided by 0.5% bupivacaine and 0.75% ropivacaine. Methods: A total of 80 patients were included in the study. After obtaining informed and written consent from patient, we randomized patients into two groups. Group B received 5 mL (1:1 mixture) of 0.5% Bupivacaine (ANAWIN 0.5%, NEON LABORATORIES LTD), 2% Lidocaine (XYLOCAINE ® 2%, AKUMS DRUGS and PHARMACEUTICALS LTD), 1500IU of Hyaluronidase (HYNIDASE, SHREYAS LIFE SCIENCES PVT LTD) while group R received 5 mL (1:1 mixture) 0.75% Ropivacaine (ROPIN 0.75%, NEON LABORATORIES LTD), 2% lidocaine, 1500IU of Hyaluronidase. Results: In this study of 80 patients undergoing small incision cataract surgery, Group B received a bupivacaine-lidocaine-hyaluronidase mixture, while Group R received a ropivacaine-lidocaine-hyaluronidase mixture for peribulbar block. Ropivacaine showed statistically significant advantages in faster motor block onset, lower IOP after 10 min, and longer analgesia duration, with no difference in sensory block onset. Thus, ropivacaine appears to be a safer and effective alternative to bupivacaine in peribulbar anesthesia for cataract surgery. Conclusion: The analysis showed that 0.75% Ropivacaine recorded an earlier onset of motor block, low IO P value post block, and longer duration of analgesia than 0.5% Bupivacaine that was statistically significant. Hence, Ropivacaine can be used as a safer alternative for Bupivacaine in peribulbar block for cataract Surgery.

Journal of Dr NTR University of Health SciencesVol. 15(1)
Academy of Medical Sciences (GB)
Openalex Percentile: Top 9%
Intraocular Surgery and Lenses
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Comparison of 2% lidocaine and 0.5% bupivacaine with 2% lidocaine and 0.75% ropivacaine in peribulbar block for cataract surgery — Doni Akshitha, Pakalapati Pradeep, et al. · Journal of Dr NTR University of Health Sciences (2026) | TGRS Research Map | TGRS