Cervicovaginal detection of genital mycoplasmas is associated with preterm birth and low birth weight: a systematic review and multivariate meta-analysis of adverse pregnancy outcomes

Associations between genital mycoplasmas and adverse pregnancy outcomes are not limited to intraamniotic presence but are also observed with cervicovaginal detection. Given the observational nature of the available data and residual confounding, these associations should be interpreted cautiously and do not support routine screening or treatment. Cervicovaginal detection should be interpreted within the broader context of the vaginal microbial environment rather than as evidence of an isolated pathogenic effect.