Prediction of Osteoporosis and Fragility Fracture Risk Using Proximal Humerus CT Value from Chest CT: A Development and Validation Study
The Clinical + CT model, which integrates clinical factors with proximal humerus CT values from routine chest CT scans, can effectively identify individuals with osteoporosis and high fracture risk, offering a simple and effective tool for opportunistic screening. The models demonstrate good reliability, and decision curve analysis indicates a high net clinical benefit for both endpoints.
Authors
- Mingyu Zou (ORCID: https://orcid.org/0000-0002-9031-0162)
- Ben-qiang Yang (ORCID: https://orcid.org/0000-0002-3848-4667)
- Xiao Feng (ORCID: https://orcid.org/0009-0006-6267-466X)
- Yu Sun
- Xiao-Gang Li
- Chen-Xu Zhao
- Dong Han
- Ren-An Wang
- Li-Bo Zhang
Institutions
- Dalian Medical University (CN)
- Xerox (France) (FR)
- Third People 's Hospital of Liaoyang (CN)
- General Hospital of Shenyang Military Region (CN)
- The Central Hospital of Shaoyang (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- Academic Radiology
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1016/j.acra.2026.03.001
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00