GLP-1 Receptor Agonists and Long-Term Survival After Spontaneous Intracerebral Hemorrhage in Type 2 Diabetes

In this large real-world cohort of sICH survivors with T2DM, post-hemorrhage GLP-1 RA use was associated with lower long-term all-cause mortality. Given the observational design, causality cannot be inferred. These findings provide hypothesis-generating evidence supporting further prospective studies to clarify the role of GLP-1 RAs in post-sICH secondary prevention.

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Publication Details

Journal
World Neurosurgery
Published
2026-03-01
DOI
https://doi.org/10.1016/j.wneu.2026.124932
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
Field-Weighted Citation Impact
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article

GLP-1 Receptor Agonists and Long-Term Survival After Spontaneous Intracerebral Hemorrhage in Type 2 Diabetes

Yu Chang, Xiajie Lyu, Chien-Min Chen, Hong-Min Lin
World Neurosurgery
Intracerebral and Subarachnoid Hemorrhage Research
article

GLP-1 Receptor Agonists and Long-Term Survival After Spontaneous Intracerebral Hemorrhage in Type 2 Diabetes

Yu Chang, Xiajie Lyu, Chien-Min Chen, Hong-Min Lin
article en

Abstract

In this large real-world cohort of sICH survivors with T2DM, post-hemorrhage GLP-1 RA use was associated with lower long-term all-cause mortality. Given the observational design, causality cannot be inferred. These findings provide hypothesis-generating evidence supporting further prospective studies to clarify the role of GLP-1 RAs in post-sICH secondary prevention.

World Neurosurgery
Jacobi Medical Center (US), Chi Mei Medical Center (TW), National Cheng Kung University Hospital (TW), Changhua Christian Hospital (TW)
Openalex Percentile: Top 16%
Intracerebral and Subarachnoid Hemorrhage Research
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