Frequency Of Macrolide Resistance Gene MsrA In Clinically Isolated Erythromycin Resistant Staphylococcus Aureus Strains From A Tertiary Care Setting In Sindh, Pakistan

Based on the results, it was concluded that msrA is a significant contributor to the macrolide resistance in locally isolated clinical strains. A major clinical implication of this finding could be the use of efflux pump inhibitors with the macrolides may increase the sensitivity of the bacteria to the drugs, with favorable clinical outcomes.