Gastric MALT Lymphoma in Plummer-Vinson Syndrome: Broadening the Spectrum of Associated Malignancies

Plummer-Vinson syndrome (PVS) is a constellation of symptoms associated with iron deficiency anemia, esophageal web formation, and squamous cell cancer, typically of the esophagus and pharynx. PVS has rarely been associated with gastric cancer. We report a case of a 59-year-old man found to have PVS with gastric mucosa-associated lymphoid tissue lymphoma, an association to our knowledge not previously described in the literature. This case expands the spectrum of malignancies that may be encountered in patients with PVS and highlights the importance of thorough evaluation for malignancy in patients presenting with iron deficiency anemia.