Improving the estimation of population iodine status: A new method for calculating the precision and subgroup differences of median urinary iodine concentration from spot urine specimens
The Box-Cox transformation enables the calculation of results which account for complex sampling, and enables the estimation of the statistical significance of apparent subgroup differences and offers a more accurate approach to analyzing skewed UIC data. Program planners can use this approach to prioritize population groups with insufficient iodine status and tailor nutrition programs to address inequities in iodine nutrition.
Authors
- Werner Schultink (ORCID: https://orcid.org/0000-0002-5357-5305)
- Fabian Rohner (ORCID: https://orcid.org/0000-0003-0579-6952)
- Fakhriddin Nizamov
- Aminata Shamit Koroma (ORCID: https://orcid.org/0000-0001-9288-8542)
- Bradley A. Woodruff (ORCID: https://orcid.org/0000-0002-1921-5592)
- James P. Wirth (ORCID: https://orcid.org/0000-0002-4733-0379)
- Omar Obeid (ORCID: https://orcid.org/0000-0002-7554-1296)
- Arnold Timmer (ORCID: https://orcid.org/0000-0001-6672-3867)
- Nicolai Petry
- Bakary Jallow
- Ranjan Jha (ORCID: https://orcid.org/0000-0002-4741-0475)
- Maguette Beye
- Valeria Galetti
- Janet M. Peerson
- Bermet Sydygalieva
- Maria Andersson
Institutions
- Global Development Network (IN)
- Helen Keller International (US)
- Central-Asian Institute for Applied Geosciences (KG)
- Ministry of Health and Sanitation (SL)
- University Children's Hospital Zurich (CH)
- ResearchWorks (United States) (US)
- Ministry of Health and Social Welfare (GM)
- National Nutrition Agency (GM)
- National University of Uzbekistan (UZ)
- Nutrition International (CA)
- University of California, Davis (US)
- American University of Beirut (LB)
Publication Details
- Journal
- Journal of Nutrition
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1016/j.tjnut.2026.101494
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00