Echocardiographic Markers of Cardiac Response to Therapy in Patients with Light Chain Amyloidosis

Improvement in GLS correlated with improvement in RV and left atrial strain measurements in AL-CA patients receiving treatment. Changes in RV strain were seen early, within 1 year of treatment. Our study suggests that strain imaging in conjunction with cardiac biomarkers can provide a comprehensive assessment of cardiac response.

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Publication Details

Journal
Echocardiography
Published
2026-03-01
DOI
https://doi.org/10.1111/echo.70428
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Echocardiographic Markers of Cardiac Response to Therapy in Patients with Light Chain Amyloidosis

James F. Sanchez, Carlos Gomez Luna, Huiyan Ma, Shujuan Wu et al.
Echocardiography
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Echocardiographic Markers of Cardiac Response to Therapy in Patients with Light Chain Amyloidosis

James F. Sanchez, Carlos Gomez Luna, Huiyan Ma, Shujuan Wu, Sarah Lee, Faizi Jamal, Daniel Ng, Michael Rosenzweig
article en

Abstract

Improvement in GLS correlated with improvement in RV and left atrial strain measurements in AL-CA patients receiving treatment. Changes in RV strain were seen early, within 1 year of treatment. Our study suggests that strain imaging in conjunction with cardiac biomarkers can provide a comprehensive assessment of cardiac response.

EchocardiographyVol. 43(3)
City Of Hope National Medical Center (US), City of Hope (US), Hope Foundation (US)
Sustainable cities and communities
Openalex Percentile: Top 9%
Amyloidosis: Diagnosis, Treatment, Outcomes
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