Pharmacokinetic variability and complex two‐way interactions with cenobamate in patients with refractory epilepsy

We demonstrate complex and unpredictable two-way interactions in polytherapy with CNB and pronounced pharmacokinetic variability among patients with refractory epilepsy, elucidating the usefulness of TDM.

Publication Details

Journal
Epilepsia
Published
2026-03-24
DOI
https://doi.org/10.1002/epi.70184
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacokinetic variability and complex two‐way interactions with cenobamate in patients with refractory epilepsy

Epilepsia
Epilepsy research and treatment
article

Pharmacokinetic variability and complex two‐way interactions with cenobamate in patients with refractory epilepsy

article en

Abstract

We demonstrate complex and unpredictable two-way interactions in polytherapy with CNB and pronounced pharmacokinetic variability among patients with refractory epilepsy, elucidating the usefulness of TDM.

Epilepsia
Openalex Percentile: Top 19%
Epilepsy research and treatment
DOISourceOpenAlex
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Pharmacokinetic variability and complex two‐way interactions with cenobamate in patients with refractory epilepsy · Epilepsia (2026) | TGRS Research Map | TGRS