IFN-γ induces hematopoietic stem cell myelopoiesis through Meis1 in tumor

Our results highlight HSC-directed therapy as a novel approach for cancer treatment. Combining anti-PD-1 with Emapalumab potently enhances the response to ICB, offering a promising strategy to achieve superior and durable anticancer efficacy.

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Publication Details

Journal
Stem Cell Research & Therapy
Published
2026-03-24
DOI
https://doi.org/10.1186/s13287-026-04968-9
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

IFN-γ induces hematopoietic stem cell myelopoiesis through Meis1 in tumor

Stem Cell Research & Therapy
Immune cells in cancer
article

IFN-γ induces hematopoietic stem cell myelopoiesis through Meis1 in tumor

article en

Abstract

Our results highlight HSC-directed therapy as a novel approach for cancer treatment. Combining anti-PD-1 with Emapalumab potently enhances the response to ICB, offering a promising strategy to achieve superior and durable anticancer efficacy.

Stem Cell Research & Therapy
Sun Yat-sen University (CN), The Seventh Affiliated Hospital of Sun Yat-sen University (CN), Guangzhou First People's Hospital (CN), Shenzhen Children's Hospital (CN), South China Institute of Collaborative Innovation (CN), South China University of Technology (CN), Guangzhou Medical University (CN)
Openalex Percentile: Top 9%
Immune cells in cancer
DOIOpen Access PDFOpenAlex
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