The genetics of multiple sclerosis: an updated perspective
Advances in genetics are broadening the conceptual framework of MS pathogenesis, separating the immunological triggers of disease susceptibility from distinct, CNS-specific drivers of disease progression. Future efforts leveraging longitudinal, deeply phenotyped cohorts and functional validations will empower translational applications for prevention, prognostication, and treatment.
Authors
- Sergio E. Baranzini (ORCID: https://orcid.org/0000-0003-0067-194X)
- Gianmarco Bellucci
Institutions
- University of California, San Francisco (US)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Current Opinion in Neurology
- Published
- 2026-03-24
- DOI
- https://doi.org/10.1097/wco.0000000000001478
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00