Clinicopathological Characteristics of Lesions Diagnosed by MRI-Guided Biopsy in BRCA1/2 Mutation Carriers

MRI-guided biopsy was effective in detecting early-stage invasive carcinoma in <i>BRCA1/2</i> carriers, highlighting its role in tailored surveillance strategies. For new lesions categorized as breast imaging reporting and data system 3 on MRI, biopsy should be considered, particularly for <i>BRCA1/2</i> carriers. Prospective studies are needed to validate these findings and assess long-term clinical outcomes to inform personalized management approaches for high-risk populations.

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Publication Details

Journal
European Journal of Breast Health
Published
2026-03-24
DOI
https://doi.org/10.4274/ejbh.galenos.2025.2025-5-8
Primary Topic
BRCA gene mutations in cancer
Type
article
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article

Clinicopathological Characteristics of Lesions Diagnosed by MRI-Guided Biopsy in BRCA1/2 Mutation Carriers

European Journal of Breast Health
BRCA gene mutations in cancer
article

Clinicopathological Characteristics of Lesions Diagnosed by MRI-Guided Biopsy in BRCA1/2 Mutation Carriers

article en

Abstract

MRI-guided biopsy was effective in detecting early-stage invasive carcinoma in <i>BRCA1/2</i> carriers, highlighting its role in tailored surveillance strategies. For new lesions categorized as breast imaging reporting and data system 3 on MRI, biopsy should be considered, particularly for <i>BRCA1/2</i> carriers. Prospective studies are needed to validate these findings and assess long-term clinical outcomes to inform personalized management approaches for high-risk populations.

European Journal of Breast HealthVol. 22(2)
SHOWA Medical University (JP), National Sagamihara Hospital (JP)
Good health and well-being
Openalex Percentile: Top 10%
BRCA gene mutations in cancer
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