Prospective head-to-head comparison of routine non-invasive scores for predicting severe cirrhosis-related morbidity in the general population

CORE and LiverRisk are the most discriminative routine blood-based tools for predicting long-term cirrhosis-related morbidity in the community. When referrals are limited, a higher-threshold CORE-only strategy may outperform a sequential CORE-LiverRisk approach.

Authors

Huizhen Jin (ORCID: https://orcid.org/0000-0002-9399-9268)
Wenhui Gao (ORCID: https://orcid.org/0000-0001-9501-885X)
Haitao Zhang (ORCID: https://orcid.org/0000-0002-1639-4089)
Yawen Liu (ORCID: https://orcid.org/0000-0003-2859-4771)
Y. H. Cheng
Jikang Shi
Xinmeng Hu
Zhuoshuai Liang
Yingao Xi

Institutions

Jilin University (CN)
First Hospital of Jilin University (CN)
Peking University Shenzhen Hospital (CN)
University of Hong Kong - Shenzhen Hospital (CN)

Publication Details

Journal: Hepatology
Published: 2026-03-23
DOI: https://doi.org/10.1097/hep.0000000000001749
Primary Topic: Liver Disease and Transplantation
Type: article
Field-Weighted Citation Impact: 0.00

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article

Prospective head-to-head comparison of routine non-invasive scores for predicting severe cirrhosis-related morbidity in the general population

Huizhen Jin, Wenhui Gao, Haitao Zhang, Yawen Liu et al.

Mar 23, 2026

Hepatology

Liver Disease and Transplantation

article

Prospective head-to-head comparison of routine non-invasive scores for predicting severe cirrhosis-related morbidity in the general population

Huizhen Jin, Wenhui Gao, Haitao Zhang, Yawen Liu, Y. H. Cheng, Jikang Shi, Xinmeng Hu, Zhuoshuai Liang, Yingao Xi

March 23, 2026article en

Abstract

CORE and LiverRisk are the most discriminative routine blood-based tools for predicting long-term cirrhosis-related morbidity in the community. When referrals are limited, a higher-threshold CORE-only strategy may outperform a sequential CORE-LiverRisk approach.

Hepatology

Jilin University (CN), First Hospital of Jilin University (CN), Peking University Shenzhen Hospital (CN), University of Hong Kong - Shenzhen Hospital (CN)

Reduced inequalities, Peace, Justice and strong institutions

Openalex Percentile: Top 10%

Liver Disease and Transplantation

DOI Source OpenAlex

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Prospective head-to-head comparison of routine non-invasive scores for predicting severe cirrhosis-related morbidity in the general population — Huizhen Jin, Wenhui Gao, et al. · Hepatology (2026) | TGRS Research Map | TGRS