Immunocytochemical Analysis of Stem Cell Markers in Pancreatic Adenocarcinoma

OCT4 expression is a specific biomarker for PDAC. Its increased expression signified PDAC progression and CD24 activation in a subset of PDAC. KRAS mutants have lower OCT4 expression, suggesting an alternative mechanism for cancer progression than that in OCT4 positive PDAC.

Publication Details

Journal
Cytopathology
Published
2026-03-23
DOI
https://doi.org/10.1111/cyt.70072
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Immunocytochemical Analysis of Stem Cell Markers in Pancreatic Adenocarcinoma

Cytopathology
Pancreatic and Hepatic Oncology Research
article

Immunocytochemical Analysis of Stem Cell Markers in Pancreatic Adenocarcinoma

article en

Abstract

OCT4 expression is a specific biomarker for PDAC. Its increased expression signified PDAC progression and CD24 activation in a subset of PDAC. KRAS mutants have lower OCT4 expression, suggesting an alternative mechanism for cancer progression than that in OCT4 positive PDAC.

Cytopathology
Good health and well-being
Openalex Percentile: Top 10%
Pancreatic and Hepatic Oncology Research
DOISourceOpenAlex
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Immunocytochemical Analysis of Stem Cell Markers in Pancreatic Adenocarcinoma · Cytopathology (2026) | TGRS Research Map | TGRS