Dynamic changes in Lamin B1 and heterochromatin coincide with chromatin condensation during human erythropoiesis

These findings reveal a previously unrecognized regulatory axis linking H3K9me3 and chromatin-lamina interactions, providing novel insights into the spatial and temporal control of chromatin organization during erythroid development.

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Publication Details

Journal
Genome biology
Published
2026-03-24
DOI
https://doi.org/10.1186/s13059-026-04025-x
Primary Topic
Nuclear Structure and Function
Type
article
Field-Weighted Citation Impact
0.00
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article

Dynamic changes in Lamin B1 and heterochromatin coincide with chromatin condensation during human erythropoiesis

X. -G. Liu, Yijin Chen, Yiqi Li, Delin Kong et al.
Genome biology
Nuclear Structure and Function
article

Dynamic changes in Lamin B1 and heterochromatin coincide with chromatin condensation during human erythropoiesis

X. -G. Liu, Yijin Chen, Yiqi Li, Delin Kong, Dawei Huo, Qiqi Zhang, Yulin Xu, Rui Wen, Yuyang Jiang, Yingjie Lu, He Huang, Junzhe Zhu, Pengxu Qian, Meng Zhang
article en

Abstract

These findings reveal a previously unrecognized regulatory axis linking H3K9me3 and chromatin-lamina interactions, providing novel insights into the spatial and temporal control of chromatin organization during erythroid development.

Genome biology
Hangzhou Normal University (CN), Huawei Technologies (China) (CN), Immunité et Cancer (FR), Cell Technology (China) (HK), Zhejiang Lab (CN), Zhejiang University-University of Edinburgh Institute (CN), First Affiliated Hospital Zhejiang University (CN), Zhejiang University (CN)
Zero hunger
Openalex Percentile: Top 10%
Nuclear Structure and Function
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