Micronuclei and sister chromatid exchange in lymphocytes from physicians exposed to ionizing radiation

No significant differences were observed in hematological parameters between the two groups. However, the frequencies of both micronuclei and sister chromatid exchanges were significantly higher in the exposed physicians compared to the unexposed control group. Chronic occupational exposure to ionizing radiation is associated with measurable signs of genomic instability. These findings highlight the necessity of implementing regular biomonitoring programs for exposed medical personnel to detect early genetic alterations and mitigate potential health risks.

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Publication Details

Journal
BMC Research Notes
Published
2026-03-24
DOI
https://doi.org/10.1186/s13104-026-07783-w
Primary Topic
Carcinogens and Genotoxicity Assessment
Type
article
Field-Weighted Citation Impact
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article

Micronuclei and sister chromatid exchange in lymphocytes from physicians exposed to ionizing radiation

BMC Research Notes
Carcinogens and Genotoxicity Assessment
article

Micronuclei and sister chromatid exchange in lymphocytes from physicians exposed to ionizing radiation

article en

Abstract

No significant differences were observed in hematological parameters between the two groups. However, the frequencies of both micronuclei and sister chromatid exchanges were significantly higher in the exposed physicians compared to the unexposed control group. Chronic occupational exposure to ionizing radiation is associated with measurable signs of genomic instability. These findings highlight the necessity of implementing regular biomonitoring programs for exposed medical personnel to detect early genetic alterations and mitigate potential health risks.

BMC Research Notes
Universidad Autónoma de Sinaloa (MX), Autonomous University of Tamaulipas (MX)
Good health and well-being
Openalex Percentile: Top 10%
Carcinogens and Genotoxicity Assessment
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