OptiSyn: an interpretable, multi-omics–driven graph convolutional network framework for synergy-oriented drug combination design in disease treatment

The suggested AI-driven formula design approach provides new insights into combinatorial therapy approaches for AS while also conforming to the TCM theory of Jun-Chen-Zuo-Shi principle. The significant potential of combining contemporary bioinformatics and AI techniques with traditional medicine is demonstrated by this study, which could facilitate efficient and mechanistically informed disease therapy.