Alignment strategy does not confer clinically meaningful advantages in medial pivot total knee arthroplasty: a systematic review and meta-analysis
Both kinematic and mechanical alignment in medial pivot TKA yielded reliable improvements in clinical and functional outcomes, with only minor differences in motion and joint awareness that did not reach thresholds of clinical relevance. Surgical decision-making should therefore prioritise intraoperative soft tissue balance, implant-specific design, and surgeon expertise rather than the expectation of meaningful superiority of one alignment philosophy over the other.
Institutions
- Indraprastha Apollo Hospitals (IN)
- Queen Mary University of London (GB)
- University of Milan (IT)
- Mile End Hospital (GB)
- Ospedale di Bolzano (IT)
- University Hospital in Halle (DE)
- Link Campus University (IT)
- Keele University (GB)
- Martin Luther University Halle-Wittenberg (DE)
- Sapienza University of Rome (IT)
- Immersion (United States) (US)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2026-03-24
- DOI
- https://doi.org/10.1186/s13018-026-06668-9
- Primary Topic
- Total Knee Arthroplasty Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00