Alignment strategy does not confer clinically meaningful advantages in medial pivot total knee arthroplasty: a systematic review and meta-analysis

Both kinematic and mechanical alignment in medial pivot TKA yielded reliable improvements in clinical and functional outcomes, with only minor differences in motion and joint awareness that did not reach thresholds of clinical relevance. Surgical decision-making should therefore prioritise intraoperative soft tissue balance, implant-specific design, and surgeon expertise rather than the expectation of meaningful superiority of one alignment philosophy over the other.

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Publication Details

Journal
Journal of Orthopaedic Surgery and Research
Published
2026-03-24
DOI
https://doi.org/10.1186/s13018-026-06668-9
Primary Topic
Total Knee Arthroplasty Outcomes
Type
article
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article

Alignment strategy does not confer clinically meaningful advantages in medial pivot total knee arthroplasty: a systematic review and meta-analysis

Journal of Orthopaedic Surgery and Research
Total Knee Arthroplasty Outcomes
article

Alignment strategy does not confer clinically meaningful advantages in medial pivot total knee arthroplasty: a systematic review and meta-analysis

article en

Abstract

Both kinematic and mechanical alignment in medial pivot TKA yielded reliable improvements in clinical and functional outcomes, with only minor differences in motion and joint awareness that did not reach thresholds of clinical relevance. Surgical decision-making should therefore prioritise intraoperative soft tissue balance, implant-specific design, and surgeon expertise rather than the expectation of meaningful superiority of one alignment philosophy over the other.

Journal of Orthopaedic Surgery and Research
Indraprastha Apollo Hospitals (IN), Queen Mary University of London (GB), University of Milan (IT), Mile End Hospital (GB), Ospedale di Bolzano (IT), University Hospital in Halle (DE), Link Campus University (IT), Keele University (GB), Martin Luther University Halle-Wittenberg (DE), Sapienza University of Rome (IT), Immersion (United States) (US)
Gender equality
Openalex Percentile: Top 10%
Total Knee Arthroplasty Outcomes
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