Systemic Thrombolytic Resistance in Antithrombin III Deficiency Rescued by Catheter‐Directed Thrombolysis: A Case Report

This case highlights systemic thrombolysis failure associated with AT III deficiency and demonstrates that CDT can serve as an effective, low-bleeding-risk rescue therapy for extensive DVT when systemic treatment is inadequate. These findings underscore the importance of early recognition of AT III deficiency and consideration of catheter-based intervention in similar high-risk settings.

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Publication Details

Journal
Catheterization and Cardiovascular Interventions
Published
2026-03-24
DOI
https://doi.org/10.1002/ccd.70569
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Systemic Thrombolytic Resistance in Antithrombin III Deficiency Rescued by Catheter‐Directed Thrombolysis: A Case Report

Catheterization and Cardiovascular Interventions
Blood Coagulation and Thrombosis Mechanisms
article

Systemic Thrombolytic Resistance in Antithrombin III Deficiency Rescued by Catheter‐Directed Thrombolysis: A Case Report

article en

Abstract

This case highlights systemic thrombolysis failure associated with AT III deficiency and demonstrates that CDT can serve as an effective, low-bleeding-risk rescue therapy for extensive DVT when systemic treatment is inadequate. These findings underscore the importance of early recognition of AT III deficiency and consideration of catheter-based intervention in similar high-risk settings.

Catheterization and Cardiovascular Interventions
Ulsan College (KR), University of Ulsan (KR), Keimyung University Dongsan Medical Center (KR), Yeungnam University Medical Center (KR), Keimyung University (KR)
Openalex Percentile: Top 10%
Blood Coagulation and Thrombosis Mechanisms
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