Rare Vocal Cord Lesion Presenting as Shortness of Breath: Inflammatory Myofibroblastic Tumour of the Larynx

Inflammatory myofibroblastic tumours (IMTs) are rare soft tissue neoplasms of malignant potential which are infrequently encountered in the larynx. These lesions can mimic benign pathologies and present challenges in diagnosis and management due to their rarity and varied clinical presentations. We report a case of a 69‐year‐old male with a four‐year history of progressive dyspnoea and a 20‐year history of hoarseness. Flexible nasendoscopy revealed a polypoid mass on the left vocal fold. Surgical excision via microlaryngoscopy with coblation was performed without complications. Histopathology and molecular testing confirmed the diagnosis of an ALK‐positive IMT. The patient’s symptoms resolved entirely postoperatively with no evidence of recurrence at 18‐month follow‐up. This case represents the importance of histopathological analysis and multidisciplinary discussion in the management and surveillance of rare tumours. Whilst there is limited information on cancer‐specific and overall outcomes, the malignant potential of IMT has implications for the monitoring of recurrence.

Institutions

Publication Details

Journal
Case Reports in Otolaryngology
Published
2026-01-01
DOI
https://doi.org/10.1155/crot/5582256
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Rare Vocal Cord Lesion Presenting as Shortness of Breath: Inflammatory Myofibroblastic Tumour of the Larynx

Case Reports in Otolaryngology
IgG4-Related and Inflammatory Diseases
article

Rare Vocal Cord Lesion Presenting as Shortness of Breath: Inflammatory Myofibroblastic Tumour of the Larynx

article en

Abstract

Inflammatory myofibroblastic tumours (IMTs) are rare soft tissue neoplasms of malignant potential which are infrequently encountered in the larynx. These lesions can mimic benign pathologies and present challenges in diagnosis and management due to their rarity and varied clinical presentations. We report a case of a 69‐year‐old male with a four‐year history of progressive dyspnoea and a 20‐year history of hoarseness. Flexible nasendoscopy revealed a polypoid mass on the left vocal fold. Surgical excision via microlaryngoscopy with coblation was performed without complications. Histopathology and molecular testing confirmed the diagnosis of an ALK‐positive IMT. The patient’s symptoms resolved entirely postoperatively with no evidence of recurrence at 18‐month follow‐up. This case represents the importance of histopathological analysis and multidisciplinary discussion in the management and surveillance of rare tumours. Whilst there is limited information on cancer‐specific and overall outcomes, the malignant potential of IMT has implications for the monitoring of recurrence.

Case Reports in OtolaryngologyVol. 2026(1)
University of Auckland (NZ), Gosford Hospital (AU), Auckland University of Technology (NZ)
Good health and well-being
Openalex Percentile: Top 9%
IgG4-Related and Inflammatory Diseases
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.