Multidimensional Profiling of <scp>MRI</scp> ‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

These findings demonstrate that TLE-MRIneg represents a distinct clinical-imaging entity from TLE-HS. The identification of morphologically defined subtypes, particularly AE, highlights the heterogeneity of TLE-MRIneg and its potential clinical relevance. This work supports the use of advanced imaging and data-driven methods to improve diagnosis and guide individualized management in non-lesional epilepsies.

Publication Details

Journal
Annals of Clinical and Translational Neurology
Published
2026-03-24
DOI
https://doi.org/10.1002/acn3.70349
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Multidimensional Profiling of MRI ‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology
Epilepsy research and treatment
article

Multidimensional Profiling of MRI ‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

article en

Abstract

These findings demonstrate that TLE-MRIneg represents a distinct clinical-imaging entity from TLE-HS. The identification of morphologically defined subtypes, particularly AE, highlights the heterogeneity of TLE-MRIneg and its potential clinical relevance. This work supports the use of advanced imaging and data-driven methods to improve diagnosis and guide individualized management in non-lesional epilepsies.

Annals of Clinical and Translational Neurology
Openalex Percentile: Top 20%
Epilepsy research and treatment
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Multidimensional Profiling of <scp>MRI</scp> ‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes · Annals of Clinical and Translational Neurology (2026) | TGRS Research Map | TGRS