The Effect of Methylphenidate Treatment on Oxidative Stress Levels in Children Diagnosed with Attention-Deficit/Hyperactivity Disorder: An Observational Study

Three months of MPH treatment was associated with robust clinical improvement and parallel reductions in multiple oxidant and antioxidant biomarkers. Baseline OS markers may help identify children most likely to show marked symptom reduction, though findings should be interpreted cautiously, given the sample size.