The magnitude of the pharmacodynamic index for NOSO-502: pathogen clearance, emergence of resistance and human dose predictions

A combination of the use of PDI targets and prediction of human pharmacokinetics allowed effective doses of NOSO-502 in man to be estimated.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2026-03-04
DOI
https://doi.org/10.1093/jac/dkag106
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
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article

The magnitude of the pharmacodynamic index for NOSO-502: pathogen clearance, emergence of resistance and human dose predictions

Journal of Antimicrobial Chemotherapy
Antibiotics Pharmacokinetics and Efficacy
article

The magnitude of the pharmacodynamic index for NOSO-502: pathogen clearance, emergence of resistance and human dose predictions

article en

Abstract

A combination of the use of PDI targets and prediction of human pharmacokinetics allowed effective doses of NOSO-502 in man to be estimated.

Journal of Antimicrobial ChemotherapyVol. 81(4)
University of Liverpool (GB), National and Kapodistrian University of Athens (GR), Southmead Hospital (GB), Erasmus MC (NL), GGD Haaglanden (NL), Cyclopharma (France) (FR), Medical University of Vienna (AT), Evotec (United States) (US)
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Openalex Percentile: Top 10%
Antibiotics Pharmacokinetics and Efficacy
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