Adipose tissue microvascular is linked to insulin resistance and lipidome alterations in treated HIV
Adipose tissue microvasculature remodeling in PWH on contemporary ART was associated with changes in several plasma lipid species, which are also linked to insulin resistance. Interventions targeting adipose tissue endothelial dysfunction may improve metabolic health in PWH on long-term ART.
Authors
- LaToya Hannah (ORCID: https://orcid.org/0000-0002-1676-1096)
- Jonathan A. Kropski (ORCID: https://orcid.org/0000-0002-8923-1344)
- Samuel Bailin (ORCID: https://orcid.org/0000-0003-4990-1013)
- Curtis L. Gabriel (ORCID: https://orcid.org/0000-0002-1611-3136)
- Celestine N. Wanjalla (ORCID: https://orcid.org/0000-0001-9159-5414)
- Mona Mashayekhi (ORCID: https://orcid.org/0000-0003-0331-2395)
- Rama Gangula
- Run Fan
- Fei Ye
- John R. Koethe
Institutions
- Vanderbilt University (US)
- VA Tennessee Valley Healthcare System (US)
- Geriatric Research Education and Clinical Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- AIDS
- Published
- 2026-03-24
- DOI
- https://doi.org/10.1097/qad.0000000000004491
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00