Longitudinal Safety Outcomes of Anti-tumor Necrosis Factor Alpha Therapy in the Treatment of Inflammatory Bowel Disease

Long-term anti-TNF therapy appears to have a similar safety profile to short-term therapy, with no significant increase in overall AE risk. These findings may offer cautious reassurance regarding extended anti-TNF use, particularly in patients with CD on infliximab.

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Publication Details

Journal
Digestive Diseases and Sciences
Published
2026-03-24
DOI
https://doi.org/10.1007/s10620-026-09797-7
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal Safety Outcomes of Anti-tumor Necrosis Factor Alpha Therapy in the Treatment of Inflammatory Bowel Disease

Digestive Diseases and Sciences
Inflammatory Bowel Disease
article

Longitudinal Safety Outcomes of Anti-tumor Necrosis Factor Alpha Therapy in the Treatment of Inflammatory Bowel Disease

article en

Abstract

Long-term anti-TNF therapy appears to have a similar safety profile to short-term therapy, with no significant increase in overall AE risk. These findings may offer cautious reassurance regarding extended anti-TNF use, particularly in patients with CD on infliximab.

Digestive Diseases and Sciences
University of California, Los Angeles (US)
Good health and well-being
Openalex Percentile: Top 10%
Inflammatory Bowel Disease
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Longitudinal Safety Outcomes of Anti-tumor Necrosis Factor Alpha Therapy in the Treatment of Inflammatory Bowel Disease · Digestive Diseases and Sciences (2026) | TGRS Research Map | TGRS