Guinea Pigs and Semplica Girls: On Degradation, Exploitation, and Clinical Research

abstract: Drawing on George Saunders's short story "The Semplica-Girl Diaries," this essay explores the concept of degradation in Phase 1 clinical trials. It examines the morality of paying a person to allow themselves to be used instrumentally and how the problem of degradation might be remedied.

Authors

Publication Details

Journal
Perspectives in biology and medicine
Published
2026-01-01
DOI
https://doi.org/10.1353/pbm.2026.a985810
Primary Topic
Posthumanist Ethics and Activism
Type
article
Field-Weighted Citation Impact
0.00
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article

Guinea Pigs and Semplica Girls: On Degradation, Exploitation, and Clinical Research

Carl Elliott
Perspectives in biology and medicine
Posthumanist Ethics and Activism
article

Guinea Pigs and Semplica Girls: On Degradation, Exploitation, and Clinical Research

Carl Elliott
article en

Abstract

abstract: Drawing on George Saunders's short story "The Semplica-Girl Diaries," this essay explores the concept of degradation in Phase 1 clinical trials. It examines the morality of paying a person to allow themselves to be used instrumentally and how the problem of degradation might be remedied.

Perspectives in biology and medicineVol. 69(1)
Gender equality
Openalex Percentile: Top 12%
Posthumanist Ethics and Activism
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Guinea Pigs and Semplica Girls: On Degradation, Exploitation, and Clinical Research — Carl Elliott · Perspectives in biology and medicine (2026) | TGRS Research Map | TGRS