Endometrial Cancer Diagnosis During IVF Treatment With Subsequent Live Birth Following Fertility‐Sparing Approach: A Case Report

The incidence of endometrial cancer has been increasing, with up to 14% of cases occurring in women of reproductive age. Many younger women with endometrial cancer may not present with typical risk factors such as obesity or polycystic ovary syndrome (PCOS). Hysterectomy is considered the gold standard treatment for endometrial cancer; however, this is challenging for women who wish to preserve their fertility. Fertility‐sparing treatments can be offered in early‐stage disease with a favourable prognosis in women of reproductive age. Surveillance and compliance with treatment are paramount for positive treatment outcomes. We report a case of a woman who was diagnosed with endometrial cancer during in vitro fertilisation (IVF) treatment and subsequently achieved a live birth following complete disease regression with fertility‐sparing treatment. We discuss the importance of investigating women of reproductive age, especially those with a history of subfertility, and the provision of fertility‐sparing treatment.

Publication Details

Journal
Case Reports in Obstetrics and Gynecology
Published
2026-01-01
DOI
https://doi.org/10.1155/crog/1492522
Primary Topic
Gynecological conditions and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Endometrial Cancer Diagnosis During IVF Treatment With Subsequent Live Birth Following Fertility‐Sparing Approach: A Case Report

Case Reports in Obstetrics and Gynecology
Gynecological conditions and treatments
article

Endometrial Cancer Diagnosis During IVF Treatment With Subsequent Live Birth Following Fertility‐Sparing Approach: A Case Report

article en

Abstract

The incidence of endometrial cancer has been increasing, with up to 14% of cases occurring in women of reproductive age. Many younger women with endometrial cancer may not present with typical risk factors such as obesity or polycystic ovary syndrome (PCOS). Hysterectomy is considered the gold standard treatment for endometrial cancer; however, this is challenging for women who wish to preserve their fertility. Fertility‐sparing treatments can be offered in early‐stage disease with a favourable prognosis in women of reproductive age. Surveillance and compliance with treatment are paramount for positive treatment outcomes. We report a case of a woman who was diagnosed with endometrial cancer during in vitro fertilisation (IVF) treatment and subsequently achieved a live birth following complete disease regression with fertility‐sparing treatment. We discuss the importance of investigating women of reproductive age, especially those with a history of subfertility, and the provision of fertility‐sparing treatment.

Case Reports in Obstetrics and GynecologyVol. 2026(1)
Good health and well-being
Openalex Percentile: Top 9%
Gynecological conditions and treatments
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Endometrial Cancer Diagnosis During IVF Treatment With Subsequent Live Birth Following Fertility‐Sparing Approach: A Case Report · Case Reports in Obstetrics and Gynecology (2026) | TGRS Research Map | TGRS