A Combinatorial Strategy for Peripheral Nerve Repair Utilizing 3D-Printed Collagen Nerve Guidance Conduits and Photobiomodulation Therapy: A Pilot Study in a Rat Sciatic Nerve Transection Model
Altogether, this study provides encouraging preliminary evidence that these novel, 3D-printed NGCs are biocompatible and promote early nerve regeneration after peripheral neurotmesis. While PBMT did not enhance outcomes in this study, further work is needed to optimize light delivery parameters and improve conduit design for enhanced neuroregeneration.
Authors
- Shailly H. Jariwala (ORCID: https://orcid.org/0000-0003-3338-2685)
- Jack T. Buchen (ORCID: https://orcid.org/0009-0009-7774-7157)
- Juanita J. Anders (ORCID: https://orcid.org/0000-0002-6696-4860)
- Christopher R. Fellin (ORCID: https://orcid.org/0000-0002-5075-1123)
- Richard C. Steiner (ORCID: https://orcid.org/0000-0002-6921-1450)
- Xiaoning Yuan
Institutions
- Henry M. Jackson Foundation (US)
- Uniformed Services University of the Health Sciences (US)
Publication Details
- Journal
- Photobiomodulation Photomedicine and Laser Surgery
- Published
- 2026-03-24
- DOI
- https://doi.org/10.1177/25785478251414510
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00