In Vivo Imaging of the Innate Immune System in the Pancreas in New‐Onset and Long‐Standing Type 1 Diabetes

PET imaging of innate immune cells in the pancreas is feasible. While no increased macrophage or neutrophil activity was observed in new-onset T1D, increased tracer uptake in long-standing T1D may reflect late-stage inflammatory processes and fibrosis.

Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-03-23
DOI
https://doi.org/10.1111/dom.70672
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
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article

In Vivo Imaging of the Innate Immune System in the Pancreas in New‐Onset and Long‐Standing Type 1 Diabetes

Diabetes Obesity and Metabolism
Diabetes and associated disorders
article

In Vivo Imaging of the Innate Immune System in the Pancreas in New‐Onset and Long‐Standing Type 1 Diabetes

article en

Abstract

PET imaging of innate immune cells in the pancreas is feasible. While no increased macrophage or neutrophil activity was observed in new-onset T1D, increased tracer uptake in long-standing T1D may reflect late-stage inflammatory processes and fibrosis.

Diabetes Obesity and Metabolism
Good health and well-being
Openalex Percentile: Top 10%
Diabetes and associated disorders
DOIOpen Access PDFOpenAlex
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In Vivo Imaging of the Innate Immune System in the Pancreas in New‐Onset and Long‐Standing Type 1 Diabetes · Diabetes Obesity and Metabolism (2026) | TGRS Research Map | TGRS