Sequencing of Pleural Fluid and Plasma for Tuberculous Pleuritis
Targeted sequencing of pleural fluid with selectively masked <i>M. tuberculosis</i> genomic alignment accurately diagnosed TBP and outperformed conventional diagnostic tests. (Supported by InnoHK and the Hong Kong Tuberculosis, Chest and Heart Diseases Association; ClinicalTrials.gov number, NCT05397730.).
Authors
- Guannan Kang (ORCID: https://orcid.org/0000-0003-1490-4193)
- P. C. Jiang
- Christopher K.C. Lai (ORCID: https://orcid.org/0000-0001-8591-5944)
- Huimin Shang
- Saravanan Ramakrishnan
- Irene O L Tse (ORCID: https://orcid.org/0000-0001-6175-9262)
- Charlotte H. Y. Lau
- Ken K. P. Chan
- Joyce Ng
- Rachel Lo
- A Lai
- Mary-Jane L. Ma
- Stephanie C. Y. Yu
- David S. C. Hui
- K. T. Wong
- Vicky C. T. Lee
- Y. M. Dennis Lo
- K. M. Chow
- Guangya Wang
- L. Y. Lois Choy
- Qing Zhou
- Charles M. L. Chan
- Angela C. Y. Leung
- W. H. Yip
- Christopher Chan
- Y. C. Gary Lee
- S. H. Cheng
- Jenny C. L. Ngai
- K. C. Allen Chan
- W. K. Jacky Lam
- K. W. To
- Crystal S. N. Tso
- Fanny W. S. Ko
- Natalie H. L. Wong
- Yasine Malki
Institutions
- Chinese University of Hong Kong (HK)
- The University of Western Australia (AU)
- Sir Charles Gairdner Hospital (AU)
- Institute for Respiratory Health (AU)
Publication Details
- Journal
- NEJM Evidence
- Published
- 2026-03-24
- DOI
- https://doi.org/10.1056/evidoa2500237
- Citations
- 1
- Primary Topic
- Pleural and Pulmonary Diseases
- Type
- article
- Field-Weighted Citation Impact
- 36.44