Advances in the management of giant cell arteritis–aortitis: biologic therapies and beyond - a narrative review

Management should follow a treat-to-target strategy aimed at achieving clinical and, when feasible, imaging remission. Although glucocorticoids remain the cornerstone of treatment, steroid-sparing approaches, particularly with tocilizumab, and emerging targeted biotherapies may improve long-term vascular outcomes and prognosis in selected patients.

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Publication Details

Journal
Expert Opinion on Biological Therapy
Published
2026-03-23
DOI
https://doi.org/10.1080/14712598.2026.2650104
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Advances in the management of giant cell arteritis–aortitis: biologic therapies and beyond - a narrative review

R. Blanco, J. Loricera, C. Secada-Gómez, A. Martín-Gutiérrez et al.
Expert Opinion on Biological Therapy
Vasculitis and related conditions
article

Advances in the management of giant cell arteritis–aortitis: biologic therapies and beyond - a narrative review

R. Blanco, J. Loricera, C. Secada-Gómez, A. Martín-Gutiérrez, Santos Castañeda
article en

Abstract

Management should follow a treat-to-target strategy aimed at achieving clinical and, when feasible, imaging remission. Although glucocorticoids remain the cornerstone of treatment, steroid-sparing approaches, particularly with tocilizumab, and emerging targeted biotherapies may improve long-term vascular outcomes and prognosis in selected patients.

Expert Opinion on Biological Therapy
Universidad de Cantabria (ES), Hospital Universitario de La Princesa (ES)
Good health and well-being
Openalex Percentile: Top 11%
Vasculitis and related conditions
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