One cell, many fates: transcriptional networks governing <scp>CD8</scp> <sup>+</sup> T cell differentiation

A recent study in Nature shows that CD8<sup>+</sup> T cell differentiation trajectories are governed by transcription factors, with distinct single-state and multi-state regulators directing cell fate decisions.

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Publication Details

Journal
Immunology and Cell Biology
Published
2026-03-24
DOI
https://doi.org/10.1111/imcb.70106
Primary Topic
T-cell and B-cell Immunology
Type
article
Field-Weighted Citation Impact
0.00
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article

One cell, many fates: transcriptional networks governing CD8 + T cell differentiation

Gabrielle T Belz, M Zeeshan Chaudhry
Immunology and Cell Biology
T-cell and B-cell Immunology
article

One cell, many fates: transcriptional networks governing CD8 + T cell differentiation

Gabrielle T Belz, M Zeeshan Chaudhry
article en

Abstract

A recent study in Nature shows that CD8<sup>+</sup> T cell differentiation trajectories are governed by transcription factors, with distinct single-state and multi-state regulators directing cell fate decisions.

Immunology and Cell Biology
The University of Queensland (AU)
Openalex Percentile: Top 10%
T-cell and B-cell Immunology
DOISourceOpenAlex
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One cell, many fates: transcriptional networks governing <scp>CD8</scp> <sup>+</sup> T cell differentiation — Gabrielle T Belz, M Zeeshan Chaudhry · Immunology and Cell Biology (2026) | TGRS Research Map | TGRS