Recurrent multiloculated cystic variant of Lhermitte-Duclos disease managed with cyst fenestration and Ommaya reservoir placement: illustrative case.
Although LDD generally follows a benign course, multiloculated cystic variants can present with progressive recurrence and neurological deterioration. This case emphasizes the importance of recognizing cystic changes in LDD and demonstrates that adequate fenestration with communication to cisternal spaces, supplemented by Ommaya reservoir placement when necessary, can provide durable disease control. https://thejns.org/doi/10.3171/CASE25907.
Authors
- Daiki Uchida (ORCID: https://orcid.org/0000-0001-7846-2393)
- Kenta Ujifuku (ORCID: https://orcid.org/0000-0003-3481-8508)
- Akemi Matsuo (ORCID: https://orcid.org/0000-0002-8049-0366)
- Yuki Matsunaga (ORCID: https://orcid.org/0000-0001-5562-9883)
- Kenta Masui (ORCID: https://orcid.org/0000-0002-5824-6690)
- Hikaru Nakamura (ORCID: https://orcid.org/0000-0002-1864-1645)
- Takeshi Hiu (ORCID: https://orcid.org/0000-0001-7090-1662)
- Masaru Takeuchi (ORCID: https://orcid.org/0000-0001-9304-4667)
- Shiro Baba (ORCID: https://orcid.org/0000-0002-4170-1802)
- Koichi Yoshida (ORCID: https://orcid.org/0000-0003-3220-5038)
- Mai Shirahama
- Yoichi Morofuji (ORCID: https://orcid.org/0000-0001-7135-2220)
- Rin YAMAGUCHI
- Takayuki Matsuo
- Yuka Ogawa
Institutions
- SHOWA Medical University (JP)
- University of Nagasaki (JP)
- Nagasaki University Hospital (JP)
- Nagasaki University (JP)
Publication Details
- Journal
- PubMed
- Published
- 2026-03-23
- DOI
- https://doi.org/10.3171/case25907
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00