From infectious disease to oncology: translating a novel glycan target into a ‘pan-cancer’ ADC

“We recently obtained the first data ... which demonstrates that the antibody reaches the tumors to a significant extent with very limited off-target binding.”Lauren Coyle, Editor, Bioconjugate Insights, speaks with Ali Salanti, Professor, University of Copenhagen, and CEO, Var2 Pharma, about the development of a new monovalent ADC with broad anti-tumor activity – from a serendipitous discovery to preparing for clinical trials.

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Publication Details

Journal
Bioconjugation Insights
Published
2026-03-24
DOI
https://doi.org/10.18609/bci.2026.011
Primary Topic
Glycosylation and Glycoproteins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

From infectious disease to oncology: translating a novel glycan target into a ‘pan-cancer’ ADC

Ali Salanti
Bioconjugation Insights
Glycosylation and Glycoproteins Research
article

From infectious disease to oncology: translating a novel glycan target into a ‘pan-cancer’ ADC

Ali Salanti
article en

Abstract

“We recently obtained the first data ... which demonstrates that the antibody reaches the tumors to a significant extent with very limited off-target binding.”Lauren Coyle, Editor, Bioconjugate Insights, speaks with Ali Salanti, Professor, University of Copenhagen, and CEO, Var2 Pharma, about the development of a new monovalent ADC with broad anti-tumor activity – from a serendipitous discovery to preparing for clinical trials.

Bioconjugation InsightsVol. 1(2)
University of Copenhagen (DK)
Openalex Percentile: Top 11%
Glycosylation and Glycoproteins Research
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From infectious disease to oncology: translating a novel glycan target into a ‘pan-cancer’ ADC — Ali Salanti · Bioconjugation Insights (2026) | TGRS Research Map | TGRS