Glutathione-responsive conjugates of hyperbranched polyoxidized glutathione and camptothecin for cancer therapy

Camptothecin (CPT) is a highly potent antitumor agent with severe systemic toxicity in clinical application. To employ the endogenous molecule of oxidized glutathione (GSSG) as carrier for CPT delivery could...

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Publication Details

Journal
Journal of Materials Chemistry B
Published
2026-01-01
DOI
https://doi.org/10.1039/d6tb00449k
Primary Topic
Dendrimers and Hyperbranched Polymers
Type
article
Field-Weighted Citation Impact
0.00
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article

Glutathione-responsive conjugates of hyperbranched polyoxidized glutathione and camptothecin for cancer therapy

Wenqian Qian, Xianghuang Mei, Boxu Liang, Xiao Duan et al.
Journal of Materials Chemistry B
Dendrimers and Hyperbranched Polymers
article

Glutathione-responsive conjugates of hyperbranched polyoxidized glutathione and camptothecin for cancer therapy

Wenqian Qian, Xianghuang Mei, Boxu Liang, Xiao Duan, Qiang Wang, yuchao lu, Wei Guo
article en

Abstract

Camptothecin (CPT) is a highly potent antitumor agent with severe systemic toxicity in clinical application. To employ the endogenous molecule of oxidized glutathione (GSSG) as carrier for CPT delivery could...

Journal of Materials Chemistry B
Good health and well-being
Openalex Percentile: Top 11%
Dendrimers and Hyperbranched Polymers
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Glutathione-responsive conjugates of hyperbranched polyoxidized glutathione and camptothecin for cancer therapy — Wenqian Qian, Xianghuang Mei, et al. · Journal of Materials Chemistry B (2026) | TGRS Research Map | TGRS