Phylogeny-informed random forests for human microbiome studies

PIRF is an extension of the Random Forest algorithm that incorporates phylogenetic tree information to improve predictive accuracy in human microbiome studies. PIRF can serve as a useful tool for microbiome-based disease diagnostics and personalized medicine. The software and tutorials are freely available as an R package, named PIRF, at https://github.com/hk1785/PIRF.