Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19

Paxlovid demonstrates organ-specific effects on the risk of PASC, with a reduction in gastrointestinal symptoms and an increased risk of eye and ear-related symptoms. In older, non-hospitalized patients, Paxlovid modestly reduces overall PASC risk. These findings highlight the complexity of antiviral therapy's long-term impact and underscore the need for further research to clarify the mechanisms underlying these outcomes.

Institutions

Publication Details

Journal
Communications Medicine
Published
2026-03-24
DOI
https://doi.org/10.1038/s43856-026-01535-4
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19

Communications Medicine
Long-Term Effects of COVID-19
article

Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19

article en

Abstract

Paxlovid demonstrates organ-specific effects on the risk of PASC, with a reduction in gastrointestinal symptoms and an increased risk of eye and ear-related symptoms. In older, non-hospitalized patients, Paxlovid modestly reduces overall PASC risk. These findings highlight the complexity of antiviral therapy's long-term impact and underscore the need for further research to clarify the mechanisms underlying these outcomes.

Communications Medicine
Brigham and Women's Hospital (US), Massachusetts General Hospital (US)
Good health and well-being
Openalex Percentile: Top 19%
Long-Term Effects of COVID-19
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19 · Communications Medicine (2026) | TGRS Research Map | TGRS