Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19
Paxlovid demonstrates organ-specific effects on the risk of PASC, with a reduction in gastrointestinal symptoms and an increased risk of eye and ear-related symptoms. In older, non-hospitalized patients, Paxlovid modestly reduces overall PASC risk. These findings highlight the complexity of antiviral therapy's long-term impact and underscore the need for further research to clarify the mechanisms underlying these outcomes.
Institutions
- Brigham and Women's Hospital (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Communications Medicine
- Published
- 2026-03-24
- DOI
- https://doi.org/10.1038/s43856-026-01535-4
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00