Safety and feasibility of the Lung Volume Reduction Reverser (LVR-R) System in patients with severe emphysema – a first-in-human pilot study

In this severely diseased and small patient cohort, LVR-R implantation was technically feasible. Complication rate was similar to other coil studies and requires a careful pre-procedure benefit-risk evaluation. Two of fourteen bilaterally treated individuals demonstrated a notable improvement in lung function.

Publication Details

Journal
Respiration
Published
2026-03-24
DOI
https://doi.org/10.1159/000551022
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
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article

Safety and feasibility of the Lung Volume Reduction Reverser (LVR-R) System in patients with severe emphysema – a first-in-human pilot study

Respiration
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Safety and feasibility of the Lung Volume Reduction Reverser (LVR-R) System in patients with severe emphysema – a first-in-human pilot study

article en

Abstract

In this severely diseased and small patient cohort, LVR-R implantation was technically feasible. Complication rate was similar to other coil studies and requires a careful pre-procedure benefit-risk evaluation. Two of fourteen bilaterally treated individuals demonstrated a notable improvement in lung function.

Respiration
Good health and well-being
Openalex Percentile: Top 11%
Chronic Obstructive Pulmonary Disease (COPD) Research
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Safety and feasibility of the Lung Volume Reduction Reverser (LVR-R) System in patients with severe emphysema – a first-in-human pilot study · Respiration (2026) | TGRS Research Map | TGRS