EXPRESS: Identification of Acetylation-Related Molecular Signatures in Knee Osteoarthritis Patients with Significant Response to Warm-Needle Acupuncture Using Machine-Learning Approaches

WNA markedly remodels peripheral-blood acetylation-related transcriptomic network in KOA and associates stronger acetylation activity with immune-cell activation. The four-gene nomogram provides both mechanistic information and possibility for individualized prediction of WNA efficacy.