Efficacy and safety of canakinumab in patients with Adult-Onset Still’s Disease: Results from an open-label Phase III study in Japan

Although the primary endpoint was not met, week 28 analysis showed that canakinumab treatment led to improvements in various efficacy outcome measures in Japanese patients with AOSD, with no unexpected safety signals.

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Publication Details

Journal
Modern Rheumatology
Published
2026-03-23
DOI
https://doi.org/10.1093/mr/roag026
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of canakinumab in patients with Adult-Onset Still’s Disease: Results from an open-label Phase III study in Japan

Modern Rheumatology
Autoimmune and Inflammatory Disorders Research
article

Efficacy and safety of canakinumab in patients with Adult-Onset Still’s Disease: Results from an open-label Phase III study in Japan

article en

Abstract

Although the primary endpoint was not met, week 28 analysis showed that canakinumab treatment led to improvements in various efficacy outcome measures in Japanese patients with AOSD, with no unexpected safety signals.

Modern Rheumatology
Kanazawa University (JP), Novartis (Switzerland) (CH), Kyorin University (JP), Keio University (JP), Hokkaido University (JP), St. Luke's International Hospital (JP), Chiba University Hospital (JP), ENT and Allergy (US), Kanazawa University Hospital (JP), Novartis (Japan) (JP), Nagasaki University (JP), Saitama Medical University (JP), Yokohama City University (JP)
Good health and well-being
Openalex Percentile: Top 11%
Autoimmune and Inflammatory Disorders Research
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